ea0041ep341 | Clinical case reports - Thyroid/Others | ECE2016
Sorkina Ekaterina
, Grebennikova Tatiana
, Belaia Janna
, Rozhinskaia Ludmila
, Koksharova Ekaterina
, Mayorov Alexandr
, Galstyan Gagik
, Shestakova Marina
, Melnichenko Galina
, Tiulpakov Anatoly
Background: Werner syndrome is a rare autosomal recessive disease caused by a mutation of the DNA helicase gene (WRN), characterized by the premature onset of multiple age-related disorders.Objective: To describe unusual multiple endocrine and metabolic disorders in three unrelated clinical cases of Werner syndrome.Methods: Three patients with obvious clinical features of premature ageing were referred to an endocrinologist due to ...